Forward Dior Angus scored on his full debut but veteran Antony Kay was sent-off as the Valiants lose 2-1 to Carlisle in their final home game of the season.
Manager Neil Aspin made three changes including handing a first League start to forward Angus. The youngster had been recalled from a loan spell at Tamworth earlier this week.
After Carlisle had the better of the opening exchanges, it was Vale who took the lead on the half-hour mark through a counter attack. Ben Whitfield played in Dan Tuner whose effort was saved but newcomer Dior Angus on hand to tap home a debut goal.
Minutes later, influential loanee Kyle Howkins was forced off with an injury and Callum Howe was given a rare opportunity.
Five minutes into the second-half Carlisle equalised with a stunning effort from Nadesan and in a poor second-half performance by Vale, Hallam Hope put the visitors into the lead on 70 minutes.
Vale’s day got worse as Antony Kay was dismissed with five minutes remaining, seemingly for arguing with the referee.
Vale: Hornby, Gibbons, Smith, Howkins (Howe), Pugh, Angus (Calveley), Kay, Whitfield, Hannant, Pope, Turner (Barnett)
Subs: Boot, Benns, Tonge, Davis
Attendance: 5,163 (540 visitors)