Bruno Ribeiro won his first competitive game at Vale Park thanks to first Vale goals for Anton Forrester and Remie Streete.
The Valiants made five changes from the side that lost to Carlisle on Tuesday with Calvin Mac-Intosch deputising for Ben Purkiss at right-back.
However, Rigino Cicilia’s home debut lasted less than ten minutes as he hobbled off with an ankle injury to be replaced by Anton Forrester.
It was a largely disjointed performance by Vale in the first period with only a couple of long-range efforts from Paulo Tavares troubling the Southend keeper. They could well have gone behind as Southend had a period of pressure in the Vale penalty area. However, the Valiants broke and Sam Foley’s great cross found the head of Anton Forrester who headed home for his first Vale goal.
The Vale were much better in the second-half and deservedly doubled their lead when Remie Streete fired home a loose ball in the penalty area.
Ribeiro’s side could have added to their lead in the closing stages with Forrester and Hooper impressive upfront. However, arguably the side’s two most impressive figures were Anthony Grant and Sam Foley in midfield who marked Ribeiro’s first win with imposing performances in the midfield.