Vale are anxiously waiting for news on the extent of the knee injury suffered by winger Enoch Andoh.
Andoh was forced off after just fourteen minutes of action during the 2-1 defeat to Colchester United.
Vale also lost winger Chris Birchall during the game to a thigh injury while Byron Moore failed a pre-match fitness test. Loan defender Ryan Inniss is back at Crystal Palace for treatment on a shoulder injury and is not likely to return until the festive period.
Manager Rob Page told the media: “We will have to assess it. He is seeing the doctor and physios and has ice on it so we will have to see the extent of it.”